Conditions & Indications

The CyberKnife system is used to treat a great variety of intracranial and extracranial indications. As a general guideline the following conditions and indications are available for procedures:

INTERCRANIAL GUIDELINES

Radiosurgery is Indicated

As an Adjunct or planned "boost" after conventional external beam radiation therapy (XRT)
As an alternative to conventional XRT, especially for radioresistant tumors
For tumor recurrence in previously irradiated Regions. These patients usually have no other Option.
As an alternative to conventional surgery:
- Equivalent outcomes in some cases
- Medical condition may preclude surgery
- Patient preference is a large factor

Benign Tumors

Meningioma
Pituitary Adenoma
Acoustic Neuroma
Other Cranial nerve Schwannomas
Glomus Jugulare Tumors
Residual/recurrent low-grade Astrocytoma Oligodendroglioma, Hemangioblastoma

Malignant Tumors

Metastatic Tumors
Malignant Gliomas

Vascular Lesions

Arteriovenous Malformations (AVM)
Cavernous Malformations/AOVM

Functional Disorders

Trigeminal Neuralgia
Cluster Headache

ENT

Recurrent or residual head and neck tumors after conventional treatment

EXTRACRANIAL GUIDELINES

Spine

Selected solitary metastases without bony spinal cord compression
Primary treatment of classically radioresistant solitary tumors, i.e. melanoma, renal cell, and sarcoma
Recurrent solitary metastases after Conventional radiotherapy

Benign Tumors

Stage I NSCLC if medically inoperable or if patient refuses open surgery
Advanced state NSCLC as a boost treatment
Up-front treatment of obstructing endobronchial lesion with post-obstructive pneumonia
Metastases: solitary or limited (2-5) multiple metastases if symptomatic or enlarging on serial imaging with a favorable survival profile

Liver

Metastases: solitary or limited (2-5) multiple metastases if symptomatic or enlarging on serial imaging with a favorable survival profile

Pancreas

Up-front radio surgery treatment of unresectable tumor "sandwiched" between chemotherapy doses
Boost treatment for persistent PET-positive region after conventional chemotherapy and radiation therapy

Renal

Renal cell cancer in medically inoperable patients

Prostate

Low-risk prostate cancer as an alternative to multi-week IMRT, low dose brachytherapy or high-dose brachytherapy (HDR)

OB-GYN

Fro vaginal cuffs as primary or as boost

Note: Other conditions may be treatable, please consult the CyberKnife Center for a recommendation.

Conditions & Indications

INTERCRANIAL GUIDELINES

Radiosurgery is Indicated

Benign Tumors

Malignant Tumors

Vascular Lesions

Functional Disorders

ENT

EXTRACRANIAL GUIDELINES

Spine

Benign Tumors

Liver

Pancreas

Renal

Prostate

OB-GYN

Additional Links

Ask the Cyberknife Team